Clare E. West

University of Oxford

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Clare

About

I am a Postdoctoral Informatics Scientist at the Structural Genomics Consortium, University of Oxford. In collaboration with the knowledge exchange network UK SPINE and Open Targets at EMBL-EBI, we aim to identify potential drug targets for age-related morbidities.

Background

SGC

NDM
Postdoctoral Informatics Scientist, Structural Genomics Consortium, University of Oxford
2020 - present

Identifying potential novel targets for age-related multimorbidities to drive new understanding of the ageing process and facilitate drug development.
Clare
DPhil Systems Approaches to Biomedical Science, University of Oxford (Lincoln College)
2015 - 2020

Exploring protein folding mechanisms to enable the protein structure prediction of previously intractable targets.
Based in the Oxford Protein Informatics Group (OPIG) in the Department of Statistics, under the supervision of Prof. Charlotte Deane and in collaboration with Jiye Shi and Sebastian Kelm at UCB Pharma.
POST Fellowship, Parliamentary Office of Science and Technology
September 2018 - January 2019

Produced a POSTnote (Parliamentary briefing) on the Cyber Security of Consumer Devices.
Three month research project, Mathematical Institute, University of Oxford
2016

Optimising anti-cancer treatment schedules to exploit competition and delay growth of therapy-resistant tumours, supervised by Prof. Helen Byrne and Prof. Eamonn Gaffney (Wolfson Centre for Mathematical Biology), Michael Davis and James Yates (AstraZeneca).
BSc (Hons) Biochemistry, University of Nottingham
2012 - 2015

Six month research project with Dr Ed Bolt, investigating the effect of a truncation mutation within the human DNA repair gene HELQ and its archaeal homologue Hel308.

Publications and Presentations

Clare E. West, Saulo H.P. de Oliveira & Charlotte M. Deane. (2019) RFQAmodel: Random Forest Quality Assessment to identify a predicted protein structure in the correct fold. PLoS ONE
[See also ISMB 2019 talk: video, slides and poster.]
Clare E. West & Lydia Harriss. (2019) Cyber Security of Consumer Devices (Parliamentary Briefing), POSTnote 593, Parliamentary Office of Science and Technology
Clare E. West, Saulo H.P. de Oliveira, Eleanor C. Law, Sebastian Kelm, Jiye Shi, Charlotte M. Deane. (2018) Efficient Sampling for the Prediction of Long and Multidomain Protein Structures (Poster), Biophysical Society 62nd Annual Meeting
Bernhard Knapp, Marta Alcala, Hao Zhang, Clare E. West, P Anton van der Merwe, Charlotte M Deane. (2018) pyHVis3D: Visualising Molecular Simulation deduced H-bond networks in 3D: Application to T-cell receptor interactions. Bioinformatics.

clare.west@sgc.ox.ac.uk